Journal article
The mechanism of HIV-1 core assembly: insights from three-dimensional reconstructions of authentic virions.
- Abstract:
-
Infectious HIV particles contain a characteristic cone-shaped core encasing the viral RNA and replication proteins. The core exhibits significant heterogeneity in size and shape, yet consistently forms a well-defined structure. The mechanism by which the core is assembled in the maturing virion remains poorly understood. Using cryo-electron tomography, we have produced three-dimensional reconstructions of authentic, unstained HIV-1. These reveal the viral morphology with unprecedented clarity...
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- Publisher copy:
- 10.1016/j.str.2005.09.010
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Bibliographic Details
- Journal:
- Structure (London, England : 1993)
- Volume:
- 14
- Issue:
- 1
- Pages:
- 15-20
- Publication date:
- 2006-01-01
- DOI:
- EISSN:
-
1878-4186
- ISSN:
-
0969-2126
- Source identifiers:
-
66461
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:66461
- UUID:
-
uuid:f3904d49-4afd-4426-aef7-8fb68c41d041
- Local pid:
- pubs:66461
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2006
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