- Abstract:
-
Identification of sequence variants robustly associated with predisposition to diabetic kidney disease (DKD) has the potential to provide insights into the pathophysiological mechanisms responsible. We conducted a genome-wide association study (GWAS) of DKD in type 2 diabetes (T2D) using eight complementary dichotomous and quantitative DKD phenotypes: the principal dichotomous analysis involved 5,717 T2D subjects, 3,345 with DKD. Promising association signals were evaluated in up to 26,827...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Accepted manuscript
- Publisher:
- American Diabetes Association Publisher's website
- Journal:
- Diabetes Journal website
- Volume:
- 67
- Issue:
- 7
- Pages:
- 1414-1427
- Publication date:
- 2018-04-27
- Acceptance date:
- 2018-03-29
- DOI:
- EISSN:
-
1939-327X
- ISSN:
-
0012-1797
- Pubs id:
-
pubs:568311
- URN:
-
uri:f3860d36-645b-4890-aee3-a8d256ea1146
- UUID:
-
uuid:f3860d36-645b-4890-aee3-a8d256ea1146
- Local pid:
- pubs:568311
- Copyright holder:
- American Diabetes Association
- Copyright date:
- 2018
- Notes:
- © 2018 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. More information is available at http://www.diabetesjournals.org/content/license. This is the accepted manuscript version of the article. The final version is available online from American Diabetes Association at: https://doi.org/10.2337/db17-0914
Journal article
A genome-wide association study of diabetic kidney disease in subjects with type 2 diabetes
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Seventh Framework Program
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Academy of Finland
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Agency for Science and Technology and Research of Singapore
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Albert Påhlsson Foundation
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Alexandra Health
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