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Parkinson's disease in a dish - Using stem cells as a molecular tool

Abstract:

Parkinson's disease (PD) is the second most common neurodegenerative disease, with a strong genetic component to both the familial and sporadic forms. The cardinal motor symptoms of the disease result from the loss of dopamine (DA) neurons in the midbrain. There is currently no cure for PD and improved methods for modelling the disease are required in order to develop more effective therapeutic interventions. Patient-derived induced pluripotent stem cells (iPSCs) carry the genetic background ...

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Authors


Badger, JL More by this author
Wade-Martins, R More by this author
Cordero-Llana, O More by this author
Hartfield, EM More by this author
Journal:
Neuropharmacology
Volume:
76
Issue:
PART A
Pages:
88-96
Publication date:
2014
DOI:
EISSN:
1873-7064
ISSN:
0028-3908
URN:
uuid:f37988e4-1989-4174-ba53-ab012b58c1b1
Source identifiers:
438751
Local pid:
pubs:438751

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