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Mitochondrial biogenesis and increased uncoupling protein 1 in brown adipose tissue of mice fed a ketone ester diet.

Abstract:

We measured the effects of a diet in which D-β-hydroxybutyrate-(R)-1,3 butanediol monoester [ketone ester (KE)] replaced equicaloric amounts of carbohydrate on 8-wk-old male C57BL/6J mice. Diets contained equal amounts of fat, protein, and micronutrients. The KE group was fed ad libitum, whereas the control (Ctrl) mice were pair-fed to the KE group. Blood d-β-hydroxybutyrate levels in the KE group were 3-5 times those reported with high-fat ketogenic diets. Voluntary food intake was reduced d...

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Publication status:
Published

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Publisher copy:
10.1096/fj.11-200410

Authors


Journal:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology More from this journal
Volume:
26
Issue:
6
Pages:
2351-2362
Publication date:
2012-06-01
DOI:
EISSN:
1530-6860
ISSN:
0892-6638
Language:
English
Keywords:
Pubs id:
pubs:340198
UUID:
uuid:f3731352-3094-4a03-a954-f90f8d1105de
Local pid:
pubs:340198
Source identifiers:
340198
Deposit date:
2013-11-16

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