- Abstract:
-
To determine the aetiopathology of post-irradiation growth hormone (GH) deficiency, we performed a mixed longitudinal analysis of 56 24 h serum GH concentration profiles and 45 paired insulin-induced hypoglycaemia tests (ITT) in 35 prepubertal children, aged 1.5-11.8 years, with brain tumours in the posterior fossa (n = 25) or cerebral hemispheres (n = 10). Assessments were made before (n = 16), 1 year (n = 25) and 2 to 5 years (n = 15) after a cranial irradiation (DXR) dose of at least 30 Gy...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1677/joe.0.1500329
-
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- Journal:
- The Journal of endocrinology
- Volume:
- 150
- Issue:
- 2
- Pages:
- 329-342
- Publication date:
- 1996-08-05
- DOI:
- EISSN:
-
1479-6805
- ISSN:
-
0022-0795
- URN:
-
uuid:f36abca1-eef3-4c46-af13-34a9edcadd4c
- Source identifiers:
-
72960
- Local pid:
- pubs:72960
- Copyright date:
- 1996
Journal article
Evolution of growth hormone neurosecretory disturbance after cranial irradiation for childhood brain tumours: a prospective study.
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