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Affordable in-house antiretroviral drug resistance assay with good performance in non-subtype B HIV-1.

Abstract:

The introduction of antiretroviral (ARV) therapy in resource-poor settings is effective in suppressing HIV-1 replication and prolonging life of infected individuals. This has led to a demand for affordable HIV-1 drug resistance assays, since treatment failure due to development of drug resistance is common. This study developed and evaluated an affordable "in-house" genotyping assay to monitor HIV-1 drug resistance in Africa, particularly South Africa. An "in-house" assay using automated RNA ...

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Publication status:
Published

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Authors


Wallis, CL More by this author
Papathanasopoulos, MA More by this author
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Journal:
Journal of virological methods
Volume:
163
Issue:
2
Pages:
505-508
Publication date:
2010-02-05
DOI:
EISSN:
1879-0984
ISSN:
0166-0934
URN:
uuid:f366ae8d-20f3-4c96-b11a-d7e84ba64ce3
Source identifiers:
80635
Local pid:
pubs:80635

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