Journal article

Ion mobility-mass spectrometry of a rotary ATPase reveals ATP-induced reduction in conformational flexibility.

Abstract:: Rotary ATPases play fundamental roles in energy conversion as their catalytic rotation is associated with interdomain fluctuations and heterogeneity of conformational states. Using ion mobility mass spectrometry we compared the conformational dynamics of the intact ATPase from Thermus thermophilus with those of its membrane and soluble subcomplexes. Our results define regions with enhanced flexibility assigned to distinct subunits within the overall assembly. To provide a structural context f...
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Publication status:: Published

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APA Style

Zhou, M., Politis, A., Davies, R., Liko, I., Wu, K., Stewart, A., Stock, D., & Robinson, C. (2014). Ion mobility-mass spectrometry of a rotary ATPase reveals ATP-induced reduction in conformational flexibility. Nature Chemistry, 6(3), 208–215.

MLA Style

Zhou, M., et al. “Ion Mobility-Mass Spectrometry of a Rotary ATPase Reveals ATP-Induced Reduction in Conformational Flexibility.” Nature Chemistry, vol. 6, no. 3, 2014, pp. 208–15.

Chicago Style

Zhou, M, A Politis, R Davies, I Liko, K Wu, A Stewart, D Stock, and C Robinson. 2014. “Ion Mobility-Mass Spectrometry of a Rotary ATPase Reveals ATP-Induced Reduction in Conformational Flexibility.” Nature Chemistry 6 (3): 208–15.
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Publisher copy:: 10.1038/nchem.1868

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+ Zhou, M More by this author

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+ Politis, A More by this author

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+ Davies, R More by this author

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+ Liko, I More by this author

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+ Wu, K More by this author

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Bibliographic Details

Journal:: Nature chemistry More from this journal
Volume:: 6
Issue:: 3
Pages:: 208-215
Publication date:: 2014-03-01
DOI:: 10.1038/nchem.1868
EISSN:: 1755-4349
ISSN:: 1755-4330

Item Description

Language:: English
Keywords:: Adenosine Triphosphatases

Ions

Models, Molecular

Nucleotides

Mass Spectrometry

Molecular Conformation
Pubs id:: pubs:449257
UUID:: uuid:f35512c0-9c2c-4fa4-850b-041ce0b7f21f
Local pid:: pubs:449257
Source identifiers:: 449257
Deposit date:: 2014-02-24

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Copyright date:: 2014

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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