Journal article

Applications of RNA interference high-throughput screening technology in cancer biology and virology.

Abstract:: RNA interference (RNAi) is an ancient intra-cellular mechanism that regulates gene expression and cell function. Large-scale gene silencing using RNAi high-throughput screening (HTS) has opened an exciting frontier to systematically study gene function in mammalian cells. This approach enables researchers to identify gene function in a given biological context and will provide considerable novel insight. Here, we review RNAi HTS strategies and applications using case studies in cancer biology and virology.

Publication status:: Published

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APA Style

Gao, S., Yang, C., Jiang, S., Xu, X., Lu, X., He, Y., Cheung, A., & Wang, H. (2014). Applications of RNA interference high-throughput screening technology in cancer biology and virology. Protein and Cell, 5(11), 805–815.

MLA Style

Gao, S, et al. “Applications of RNA Interference High-Throughput Screening Technology in Cancer Biology and Virology.” Protein and Cell, vol. 5, no. 11, 2014, pp. 805–15.

Chicago Style

Gao, S, C Yang, S Jiang, et al. 2014. “Applications of RNA Interference High-Throughput Screening Technology in Cancer Biology and Virology.” Protein and Cell 5 (11): 805–15.
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Publisher copy:: 10.1007/s13238-014-0076-6

Authors

+ Gao, S More by this author

Role:: Author

+ Yang, C More by this author

Role:: Author

+ Jiang, S More by this author

Role:: Author

+ Xu, X More by this author

Role:: Author

+ Lu, X More by this author

Institution:: University of Oxford
Division:: MSD
Department:: NDM
Sub department:: Oxford Ludwig Institute
Role:: Author

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Journal:: Protein and cell More from this journal
Volume:: 5
Issue:: 11
Pages:: 805-815
Publication date:: 2014-11-01
DOI:: 10.1007/s13238-014-0076-6
EISSN:: 1674-8018
ISSN:: 1674-800X

Language:: English
Keywords:: short hairpin RNA (shRNA)

virology

RNA interference (RNAi)

cancer

short interfering RNA (siRNA)

high-throughput screening
Pubs id:: pubs:470974
UUID:: uuid:f34c27d6-dc59-4e2f-a297-7f0a28970068
Local pid:: pubs:470974
Source identifiers:: 470974
Deposit date:: 2014-07-11
ARK identifier:: ark:/29072/ora_f34c27d6dc594e2fa2977f0a28970068

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Copyright date:: 2014

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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