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Distinctive functional characteristics of human "T" lymphocytes defined by E rosetting or a monoclonal anti-T cell antibody.

Abstract:

The properties of human lymphocyte fractions isolated either by sheep red cell(E) rosetting or by fluorescence-activated cell sorting after staining with UCHT1 monoclonal anti-T cell antibody have been compared. Two populations of E+ cells with very different phenotype and function have been identified. E+/UCHT1+ cells respond well to the T cell mitogens phytohemagglutinin and concanavalin A and provide help for an in vitro specific antibody response. They can also suppress the antibody respo...

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Publisher copy:
10.1002/eji.1830110412

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division,
Callard, RE More by this author
Journal:
European journal of immunology
Volume:
11
Issue:
4
Pages:
329-334
Publication date:
1981-04-05
DOI:
EISSN:
1521-4141
ISSN:
0014-2980
URN:
uuid:f3435c67-dbc7-4aac-83a4-533eed3853e9
Source identifiers:
35534
Local pid:
pubs:35534

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