Journal article

Synthesis of taurospongin A.

Abstract:: Two new routes to the C(1-10) carboxylic acid core of taurospongin A are presented. In the first route, overall asymmetric hydration of a C(2)-C(3) alkene is achieved by Sharpless AD and selective deoxygenation at C(2); in the second route, the C(3) stereogenic center is set by Tietze asymmetric allylation. A short synthesis of the C(1'-25') fatty acid combines with the product from the first route to complete the total synthesis of taurospongin A.

Publication status:: Published

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APA Style

Wu, B., Mallinger, A., & Robertson, J. (2010). Synthesis of taurospongin A. Organic Letters, 12(12), 2818–2821.

MLA Style

Wu, B, et al. “Synthesis of Taurospongin A.” Organic Letters, vol. 12, no. 12, 2010, pp. 2818–21.

Chicago Style

Wu, B, A Mallinger, and J Robertson. 2010. “Synthesis of Taurospongin A.” Organic Letters 12 (12): 2818–21.
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Publisher copy:: 10.1021/ol100906k

Authors

+ Wu, B More by this author

Role:: Author

+ Mallinger, A More by this author

Role:: Author

+ Robertson, J More by this author

Institution:: University of Oxford
Division:: MPLS
Department:: Chemistry
Sub department:: Organic Chemistry
Role:: Author

Journal:: Organic letters More from this journal
Volume:: 12
Issue:: 12
Pages:: 2818-2821
Publication date:: 2010-06-01
DOI:: 10.1021/ol100906k
EISSN:: 1523-7052
ISSN:: 1523-7060

Language:: English
Keywords:: Alkynes

Molecular Structure

Animals

Porifera

Alkenes
Pubs id:: pubs:58736
UUID:: uuid:f33b1fa7-ac61-4f39-a906-44260d5213b6
Local pid:: pubs:58736
Source identifiers:: 58736
Deposit date:: 2012-12-19
ARK identifier:: ark:/29072/ora_f33b1fa7ac614f39a90644260d5213b6

Terms of use

Copyright date:: 2010

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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