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Protocatechuic acid promotes the neuronal differentiation and facilitates survival of phenotypes differentiated from cultured neural stem and progenitor cells.

Abstract:

Protocatechuic acid (PCA), a phenolic compound isolated from the kernels of Alpinia (A.) oxyphylla, plays crucial roles in the proliferation and neuroprotection of cultured neural stem and progenitor cells (NS/PCs) in our previous study. However, whether PCA modulates the differentiation of NS/PCs has remained to be elucidated. In this study, we show that PCA can promote the neuronal differentiation combined with fetal bovine serum (FBS) in vitro, although it cannot initiate the differentiati...

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Publication status:
Published

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Journal:
European journal of pharmacology More from this journal
Volume:
670
Issue:
2-3
Pages:
471-478
Publication date:
2011-11-01
DOI:
EISSN:
1879-0712
ISSN:
0014-2999
Language:
English
Keywords:
Pubs id:
pubs:222510
UUID:
uuid:f33affba-dfbe-43fc-9c5b-89f8b469ab22
Local pid:
pubs:222510
Source identifiers:
222510
Deposit date:
2013-11-17

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