Reciprocal interactions between the neuroendocrine and immune systems during inflammation.

Journal article

Abstract:: The neuroendocrine and immune responses to inflammatory stress represent important integrated physiologic circuits for the regulation of inflammation whose basis has been reviewed. Proinflammatory cytokines such as IL-1 beta, TNF alpha, and IL-6 released from inflammatory foci initiate a local inflammatory response and travel by way of the blood-stream to the central nervous system, where they trigger a variety of neuroendocrine counterregulatory mechanisms. There is an important NEI loop. St...
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Journal:: Rheumatic diseases clinics of North America More from this journal
Volume:: 26
Issue:: 4
Pages:: 693-711
Publication date:: 2000-11-01
DOI:: 10.1016/S0889-857X(05)70165-4
EISSN:: 1558-3163
ISSN:: 0889-857X

Language:: English
Keywords:: Neurosecretory Systems

Hypothalamus

Chronic Disease

Bacterial Infections

Inflammation

Cytokines

Humans

Immune System
Pubs id:: pubs:138318
UUID:: uuid:f32126cd-e93c-42a6-b431-83e7ecce0a29
Local pid:: pubs:138318
Source identifiers:: 138318
Deposit date:: 2012-12-19

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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