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Proteomic analysis of the cell-surface membrane in chronic lymphocytic leukemia: identification of two novel proteins, BCNP1 and MIG2B.

Abstract:

B-cell-specific plasma-membrane proteins are potential targets for either small molecule or antibody-based therapies. We have sought to annotate proteins expressed at the cell surface membrane in patients with chronic lymphocytic leukemia (CLL) using plasma-membrane-based proteomic analysis to identify previously uncharacterized and potentially B-cell-specific proteins. Proteins from plasma-membrane fractions were separated on one-dimensional gels and trypsinized fractions subjected to high-t...

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Publication status:
Published

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Publisher copy:
10.1038/sj.leu.2402993

Authors


Loader, JA More by this author
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Journal:
Leukemia
Volume:
17
Issue:
8
Pages:
1605-1612
Publication date:
2003-08-05
DOI:
EISSN:
1476-5551
ISSN:
0887-6924
URN:
uuid:f30f6aeb-d40f-4f80-a52c-34c7dc61eaae
Source identifiers:
377291
Local pid:
pubs:377291

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