Journal article
Formation of the definitive endoderm in mouse is a Smad2-dependent process.
- Abstract:
-
TGFbeta growth factors specify cell fate and establish the body plan during early vertebrate development. Diverse cellular responses are elicited via interactions with specific cell surface receptor kinases that in turn activate Smad effector proteins. Smad2-dependent signals arising in the extraembryonic tissues of early mouse embryos serve to restrict the site of primitive streak formation and establish anteroposterior identity in the epiblast. Here we have generated chimeric embryos using ...
Expand abstract
- Publication status:
- Published
Actions
Authors
Bibliographic Details
- Journal:
- Development (Cambridge, England)
- Volume:
- 127
- Issue:
- 14
- Pages:
- 3079-3090
- Publication date:
- 2000-07-01
- EISSN:
-
1477-9129
- ISSN:
-
0950-1991
- Source identifiers:
-
12783
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:12783
- UUID:
-
uuid:f30d7856-3e1e-40f6-add5-6aefef85081c
- Local pid:
- pubs:12783
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2000
If you are the owner of this record, you can report an update to it here: Report update to this record