Visual agnosia and Kluver-Bucy syndrome in marmosets (Callithrix jacchus) following ablation of inferotemporal cortex, with additional mnemonic effects of immunotoxic lesions of cholinergic projections to medial temporal areas.

Journal article

Inferotemporal ablations in the New World monkey, the common marmoset (Callithrix jacchus), produced a persistent impairment on visual discrimination learning and a florid, but transient, Klüver-Bucy syndrome. Monkeys with these ablations were impaired on acquisition of object discriminations to a high criterion and on concurrent discrimination learning, to a single high criterion across all trials. Neither the control monkeys nor the monkeys with inferotemporal ablations found acquisition mo...

Expand abstract

Authors: Ridley, R; Warner, K; Maclean, C; Gaffan, D; Baker, H

• Publication status: Published
• Journal: Brain research
• Volume: 898
• Issue: 1
• Pages: 136-151
• Publication date: 2001-04-01
• DOI: 10.1016/s0006-8993(01)02187-4
• EISSN: 1872-6240
• ISSN: 0006-8993
• Language: English
• Keywords: Animals; Callithrix; Cholinergic Fibers; Temporal Lobe; Kluver-Bucy Syndrome; Brain Diseases; Synaptic Transmission; Behavior, Animal; Oxazines; Agnosia; Coloring Agents; Immunotoxins; Female; Male; Cognition; Acetylcholinesterase; Memory; Staining and Labeling