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Journal article

Protein repeats: structures, functions, and evolution.

Abstract:

Internal repetition within proteins has been a successful strategem on multiple separate occasions throughout evolution. Such protein repeats possess regular secondary structures and form multirepeat assemblies in three dimensions of diverse sizes and functions. In general, however, internal repetition affords a protein enhanced evolutionary prospects due to an enlargement of its available binding surface area. Constraints on sequence conservation appear to be relatively lax, due to binding f...

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Publisher copy:
10.1006/jsbi.2001.4392

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Journal:
Journal of structural biology
Volume:
134
Issue:
2-3
Pages:
117-131
Publication date:
2001-01-01
DOI:
EISSN:
1095-8657
ISSN:
1047-8477
URN:
uuid:f2eae3d0-1f6f-40ed-b925-94536694a857
Source identifiers:
238076
Local pid:
pubs:238076

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