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Journal article

Ultrasound-enhanced systemic thrombolysis for acute ischemic stroke.

Abstract:

BACKGROUND: Transcranial Doppler ultrasonography that is aimed at residual obstructive intracranial blood flow may help expose thrombi to tissue plasminogen activator (t-PA). Our objective was to determine whether ultrasonography can safely enhance the thrombolytic activity of t-PA. METHODS: We treated all patients who had acute ischemic stroke due to occlusion of the middle cerebral artery with intravenous t-PA within three hours after the onset of symptoms. The patients were randomly assig...

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Publication status:
Published

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Publisher copy:
10.1056/nejmoa041175

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Journal:
New England journal of medicine
Volume:
351
Issue:
21
Pages:
2170-2178
Publication date:
2004-11-01
DOI:
EISSN:
1533-4406
ISSN:
0028-4793
Source identifiers:
199955

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