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Simulation of anisotropic growth of low-grade gliomas using diffusion tensor imaging.

Abstract:

A recent computational model of brain tumor growth, developed to better describe how gliomas invade through the adjacent brain parenchyma, is based on two major elements: cell proliferation and isotropic cell diffusion. On the basis of this model, glioma growth has been simulated in a virtual brain, provided by a 3D segmented MRI atlas. However, it is commonly accepted that glial cells preferentially migrate along the direction of fiber tracts. Therefore, in this paper, the model has been imp...

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Publisher copy:
10.1002/mrm.20625

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Mandonnet, E More by this author
Capelle, L More by this author
Swanson, KR More by this author
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Journal:
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine
Volume:
54
Issue:
3
Pages:
616-624
Publication date:
2005-09-05
DOI:
EISSN:
1522-2594
ISSN:
0740-3194
URN:
uuid:f2d4d95f-859f-4a92-9f00-2685cb451ca3
Source identifiers:
241437
Local pid:
pubs:241437

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