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Synthesis of fused tetramate-oxazolidine and -imidazolidine derivatives and their antibacterial activity

Abstract:
Chemoselective ring closure of malonamides gives oxazolidine- or imidazolidine fused tetramates, some of which show antibacterial activity against Gram positive organism; these occupy a well-defined region of chemical space.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1039/d3ob00594a

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Institution:
University of Oxford
Role:
Author
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Institution:
University of Oxford
Role:
Author
ORCID:
0000-0001-7095-1336
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Institution:
University of Oxford
Role:
Author
ORCID:
0000-0002-4061-7115
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Institution:
University of Oxford
Role:
Author
ORCID:
0000-0003-1683-2066
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Role:
Author
ORCID:
0000-0001-6854-4387



Publisher:
Royal Society of Chemistry
Journal:
Organic & Biomolecular Chemistry More from this journal
Volume:
21
Issue:
23
Pages:
4801-4809
Publication date:
2023-06-14
DOI:
EISSN:
1477-0539
ISSN:
1477-0520


Language:
English
Keywords:
Pubs id:
1346908
Local pid:
pubs:1346908
Source identifiers:
W4378347983
Deposit date:
2026-05-08
ARK identifier:
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