- Abstract:
-
Inflammation associated with nerve injury produces a number of pathogenic chemical mediators of which prostanoids are a potent component. Cyclooxygenases (Cox-1 and Cox-2) are the enzymes responsible for prostanoid production. We have investigated Cox-2 immunoreactivity (Cox-2-IR) and glial activation in human injured (n = 16) and uninjured (n = 8) nerves and in the chronic constriction injury (CCI) model of nerve injury in the rat, using immunohistological and autoradiographic methods. Tissu...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1111/j.1085-9489.2004.09104.x
-
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- Journal:
- Journal of the peripheral nervous system : JPNS
- Volume:
- 9
- Issue:
- 1
- Pages:
- 15-25
- Publication date:
- 2004-03-05
- DOI:
- EISSN:
-
1529-8027
- ISSN:
-
1085-9489
- URN:
-
uuid:f2a6b10e-b529-455b-9a30-61e7146c7ca2
- Source identifiers:
-
32623
- Local pid:
- pubs:32623
- Language:
- English
- Keywords:
- Copyright date:
- 2004
Journal article
Cyclooxygenase-2 (Cox-2) in injured human nerve and a rat model of nerve injury.
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