Journal article icon

Journal article

High-efficiency gene transfer into nontransformed cells: utility for studying gene regulation and analysis of potential therapeutic targets.

Abstract:

The elucidation of the signalling pathways involved in inflammatory diseases, such as rheumatoid arthritis, could provide long sought after targets for therapeutic intervention. Gene regulation is complex and varies depending on the cell type, as well as the signal eliciting gene activation. However, cells from certain lineages, such as macrophages, are specialised to degrade exogenous material and consequently do not easily transfect. Methods for high-efficiency gene transfer into primary ce...

Expand abstract

Actions


Access Document


Publisher copy:
10.1186/ar560

Authors


Expand authors...
Journal:
Arthritis research
Volume:
4 Suppl 3
Pages:
S215-S225
Publication date:
2002-01-01
DOI:
EISSN:
1465-9913
ISSN:
1465-9905
URN:
uuid:f2a67e03-73ac-4128-a75a-20d954cfdaa2
Source identifiers:
223481
Local pid:
pubs:223481

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP