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Journal article

Defective escape mutants of HIV.

Abstract:

The virological literature presents two broad types of defective virus mutants that can alter the outcome of viral infection. In some infections, defective interfering particles reduce the replication of wild-type virus and lead to an attenuated or persistent infection. In other cases, very specific and highly pathogenic defective mutants lead to virulent disease in the presence of a much less pathogenic but replication-competent helper virus. Here, we outline the theoretical possibility that...

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Publication status:
Published

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Publisher copy:
10.1006/jtbi.1994.1242

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Institution:
University of Oxford
Department:
Oxford, MPLS, Physics, Condensed Matter Physics
Journal:
Journal of theoretical biology
Volume:
171
Issue:
4
Pages:
387-395
Publication date:
1994-12-05
DOI:
EISSN:
1095-8541
ISSN:
0022-5193
URN:
uuid:f2a49471-1aca-431e-9402-27329dfc1e75
Source identifiers:
9441
Local pid:
pubs:9441

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