- Abstract:
-
Unlike HIV-1-infected people, most HIV-2-infected subjects maintain a healthy CD4+ T cell count and a strong HIV-specific CD4+ T cell response. To define the cellular immunological correlates of good prognosis in HIV-2 infection, we conducted a cross-sectional study of HIV Gag-specific T cell function in HIV-1- and HIV-2-infected Gambians. Using cytokine flow cytometry and lymphoproliferation assays, we show that HIV-specific CD4+ T cells from HIV-2-infected individuals maintained proliferati...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.4049/jimmunol.176.11.6973
-
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- Journal:
- Journal of immunology (Baltimore, Md. : 1950)
- Volume:
- 176
- Issue:
- 11
- Pages:
- 6973-6981
- Publication date:
- 2006-06-05
- DOI:
- EISSN:
-
1550-6606
- ISSN:
-
0022-1767
- URN:
-
uuid:f2a3e7d2-9d53-4c08-b666-45d76d4c451f
- Source identifiers:
-
8851
- Local pid:
- pubs:8851
- Language:
- English
- Keywords:
- Copyright date:
- 2006
Journal article
Maintenance of HIV-specific CD4+ T cell help distinguishes HIV-2 from HIV-1 infection.
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