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Journal article

Impact of mosquito gene drive on malaria elimination in a computational model with explicit spatial and temporal dynamics.

Abstract:

The renewed effort to eliminate malaria and permanently remove its tremendous burden highlights questions of what combination of tools would be sufficient in various settings and what new tools need to be developed. Gene drive mosquitoes constitute a promising set of tools, with multiple different possible approaches including population replacement with introduced genes limiting malaria transmission, driving-Y chromosomes to collapse a mosquito population, and gene drive disrupting a fertili...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1073/pnas.1611064114

Authors


More by this author
Institution:
University of Oxford
Oxford college:
Jesus College
Role:
Author
Publisher:
National Academy of Sciences
Journal:
Proceedings of the National Academy of Sciences More from this journal
Volume:
114
Issue:
2
Pages:
E255-E264
Publication date:
2016-12-01
Acceptance date:
2016-11-29
DOI:
EISSN:
1091-6490
Language:
English
Keywords:
Pubs id:
pubs:667649
UUID:
uuid:f29e3d95-e869-4516-9a80-725f17762823
Local pid:
pubs:667649
Source identifiers:
667649
Deposit date:
2017-05-16

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