Variability in fMRI: a re-examination of inter-session differences.

Journal article

We revisit a previous study on inter-session variability (McGonigle et al. [2000]: Neuroimage 11:708-734), showing that contrary to one popular interpretation of the original article, inter-session variability is not necessarily high. We also highlight how evaluating variability based on thresholded single-session images alone can be misleading. Finally, we show that the use of different first-level preprocessing, time-series statistics, and registration analysis methodologies can give significantly different inter-session analysis results.

Authors: Smith, S; Beckmann, C; Ramnani, N; Woolrich, M; Bannister, P

• Publication status: Published
• Journal: Human brain mapping
• Volume: 24
• Issue: 3
• Pages: 248-257
• Publication date: 2005-03-01
• DOI: 10.1002/hbm.20080
• EISSN: 1097-0193
• ISSN: 1065-9471
• Language: English
• Keywords: Artifacts; Male; Image Processing, Computer-Assisted; Brain Mapping; Head Movements; Adult; Brain; Magnetic Resonance Imaging; Humans; Reproducibility of Results