Control of intestinal inflammation by regulatory T cells.

Journal article

Regulatory T(Treg)-cell populations have been identified in a number of disease models. In this review we focus on the role of naturally occurring Treg cells in the control of intestinal inflammation. Specifically, we discuss their mechanism of action with particular emphasis on the role of anti-inflammatory cytokines and cell surface molecules.

Authors: Toms, C; Powrie, F

• Publication status: Published
• Journal: Microbes and infection / Institut Pasteur
• Volume: 3
• Issue: 11
• Pages: 929-935
• Publication date: 2001-09-01
• DOI: 10.1016/s1286-4579(01)01454-x
• EISSN: 1769-714X
• ISSN: 1286-4579
• Language: English
• Keywords: Interleukin-10; Animals; Transforming Growth Factor beta; Inflammation; Intestines; Humans; Immunity, Mucosal; T-Lymphocyte Subsets; Mice; CD4-Positive T-Lymphocytes