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Purified lymphocyte function-associated antigen-3 and T11 target structure are active in CD2-mediated T cell stimulation.

Abstract:

In this study we have used cells expressing LFA-3 or T11TS, the human and sheep forms of the ligand of CD2, as well as the purified LFA-3 and T11TS molecules themselves to study their effects on T cell activation via the CD2-mediated "alternative pathway". Sheep red blood cells, which bind to CD2 via T11TS in E-rosette formation, and human autologous monocytes, which express the LFA-3 molecule, both induce proliferation of resting T cells in the presence of per se submitogenic concentrations ...

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Publisher copy:
10.1002/eji.1830171227

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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
Journal:
European journal of immunology More from this journal
Volume:
17
Issue:
12
Pages:
1847-1850
Publication date:
1987-12-01
DOI:
EISSN:
1521-4141
ISSN:
0014-2980
Language:
English
Keywords:
Pubs id:
pubs:482718
UUID:
uuid:f2799870-b4fa-4ac1-8ba6-ea705a888323
Local pid:
pubs:482718
Source identifiers:
482718
Deposit date:
2014-09-14

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