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Journal article

Recent advances in the genetics of amyotrophic lateral sclerosis and frontotemporal dementia: common pathways in neurodegenerative disease.

Abstract:

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease classically defined by the impairment of the voluntary motor system and ubiquitin-positive intraneuronal aggregates in anterior horn cells. Frontotemporal dementia (FTD) is a common form of neurodegenerative dementia and presents with personality change associated in a significant subgroup of patients with cortical ubiquitin-only neuropathology (FTD-U). Careful study of ALS as well as FTD patient cohorts suggests clinical as w...

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Publication status:
Published

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Publisher copy:
10.1093/hmg/ddl202

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Role:
Author
Journal:
Human molecular genetics
Volume:
15 Spec No 2
Issue:
SUPPL. 2
Pages:
R182-R187
Publication date:
2006-10-05
DOI:
EISSN:
1460-2083
ISSN:
0964-6906
URN:
uuid:f274edfa-ed64-40b4-a035-cf33159555c5
Source identifiers:
242147
Local pid:
pubs:242147

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