- Abstract:
-
Mice received cytotoxic lesions which selectively removed all of the hippocampus and dentate gyrus except the most ventral portions. They were impaired on both spontaneous and rewarded discrete-trial alternation in T-mazes. Acquisition of reference memory for the location of a hidden platform in the Morris water maze was impaired in lesioned mice. On an elevated Y-maze reference memory task, in which only one arm was rewarded, lesioned mice showed no evidence of learning. In a Lashley III maz...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/s0166-4328(01)00451-x
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- Journal:
- Behavioural brain research
- Volume:
- 133
- Issue:
- 1
- Pages:
- 57-68
- Publication date:
- 2002-06-05
- DOI:
- EISSN:
-
1872-7549
- ISSN:
-
0166-4328
- URN:
-
uuid:f26715e7-c208-475f-8d29-fa3928524b2b
- Source identifiers:
-
30959
- Local pid:
- pubs:30959
- Copyright date:
- 2002
Journal article
Effects of cytotoxic hippocampal lesions in mice on a cognitive test battery.
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