Journal article icon

Journal article

Mycobacterial growth inhibition in murine splenocytes as a surrogate for protection against Mycobacterium tuberculosis (M. tb)

Abstract:

Development of an improved vaccine against tuberculosis (TB) is hindered by the lack of a surrogate of protection. Efficacy of new TB vaccines in humans can only be evaluated by expensive and time consuming efficacy trials within TB endemic areas. It is critical that vaccines with the greatest potential to protect are selected for these trials. Mycobacterial growth inhibition assays (MGIAs) have been developed with the hope that these in-vitro functional assays will correlate with protection,...

Expand abstract

Actions


Access Document


Publisher copy:
10.1016/j.tube.2013.04.007

Authors


Expand authors...
Journal:
Tuberculosis
Volume:
93
Issue:
5
Pages:
551-557
Publication date:
2013-09-05
DOI:
EISSN:
1873-281X
ISSN:
1472-9792
URN:
uuid:f253b529-dd46-4f7c-acc8-744cf5f549b0
Source identifiers:
425738
Local pid:
pubs:425738
Language:
English
Keywords:

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP