Journal article icon

Journal article

Unambiguous phosphosite localization using electron-transfer/higher-energy collision dissociation (EThcD).

Abstract:

We recently introduced a novel scheme combining electron-transfer and higher-energy collision dissociation (termed EThcD), for improved peptide ion fragmentation and identification. We reasoned that phosphosite localization, one of the major hurdles in high-throughput phosphoproteomics, could also highly benefit from the generation of such EThcD spectra. Here, we systematically assessed the impact on phosphosite localization utilizing EThcD in comparison to methods employing either ETD or HCD...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1021/pr301130k

Authors


Expand authors...
Journal:
Journal of proteome research
Volume:
12
Issue:
3
Pages:
1520-1525
Publication date:
2013-03-05
DOI:
EISSN:
1535-3907
ISSN:
1535-3893
URN:
uuid:f24e9dc4-5e97-411f-b802-511219e62db9
Source identifiers:
384543
Local pid:
pubs:384543

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP