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Serotonin receptor subtypes: implications for psychopharmacology.

Abstract:

Serotonin (5-HT) interacts with multiple brain 5-HT receptor subtypes to influence a wide range of behaviours. Three main families of 5-HT receptors (5-HT1, 5-HT2 and 5-HT3) have been described which differ in their binding affinity for selective ligands, their receptor-effector coupling mechanisms, and the behavioural processes they regulate. Nevertheless, manipulation of several different 5-HT receptor subtypes (5-HT1A, 5-HT1C, 5-HT2 and 5-HT3) may produce anxiolytic effects; 5-HT1A and 5-H...

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Publication status:
Published

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Journal:
The British journal of psychiatry. Supplement
Volume:
159
Issue:
12
Pages:
7-14
Publication date:
1991-09-05
ISSN:
0960-5371
URN:
uuid:f24db004-58d0-4de5-a226-b7f378759638
Source identifiers:
185815
Local pid:
pubs:185815

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