Journal article

Asymmetric syntheses of (-)-3-epi-Fagomine, (2R,3S,4R)-dihydroxypipecolic acid, and several polyhydroxylated homopipecolic acids.

Abstract:: A range of enantiopure polyhydroxylated piperidines, including (2R,3S,4R)-dihydroxypipecolic acid, (-)-3-epi-fagomine, (2S,3S,4R)-dihydroxyhomopipecolic acid, (2S,3R,4R)-dihydroxyhomopipecolic acid, and two trihydroxy-substituted homopipecolic acids, have been prepared using diastereoselective olefinic oxidations of a range of enantiopure tetrahydropyridines as the key step. The requisite substrates were readily prepared from tert-butyl sorbate using our diastereoselective hydroamination or a...
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APA Style

Csatayová, K., Davies, S., Fletcher, A., Ford, J., Klauber, D., Roberts, P., & Thomson, J. (2014). Asymmetric syntheses of (-)-3-epi-Fagomine, (2R,3S,4R)-dihydroxypipecolic acid, and several polyhydroxylated homopipecolic acids. Journal of Organic Chemistry, 79(22), 10932–10944.

MLA Style

Csatayová, K., et al. “Asymmetric Syntheses of (-)-3-Epi-Fagomine, (2R,3S,4R)-Dihydroxypipecolic Acid, and Several Polyhydroxylated Homopipecolic Acids.” Journal of Organic Chemistry, vol. 79, no. 22, American Chemical Society, 2014, pp. 10932–44.

Chicago Style

Csatayová, K, S Davies, A Fletcher, J Ford, D Klauber, P Roberts, and J Thomson. 2014. “Asymmetric Syntheses of (-)-3-Epi-Fagomine, (2R,3S,4R)-Dihydroxypipecolic Acid, and Several Polyhydroxylated Homopipecolic Acids.” Journal of Organic Chemistry 79 (22): 10932–44.
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Publisher copy:: 10.1021/jo501952t

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+ Csatayová, K More by this author

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+ Davies, S More by this author

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University of Oxford

Division:

MPLS

Department:

Chemistry

Sub department:

Organic Chemistry

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Author

+ Fletcher, A More by this author

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Author

+ Ford, J More by this author

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Author

+ Klauber, D More by this author

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Author

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Bibliographic Details

Publisher:: American Chemical Society
Journal:: Journal of organic chemistry More from this journal
Volume:: 79
Issue:: 22
Pages:: 10932-10944
Publication date:: 2014-11-01
DOI:: 10.1021/jo501952t
EISSN:: 1520-6904
ISSN:: 0022-3263

Item Description

Language:: English
Pubs id:: pubs:488435
UUID:: uuid:f2385bdd-454f-4381-8ba8-0e22ad4ee155
Local pid:: pubs:488435
Source identifiers:: 488435
Deposit date:: 2014-12-20

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Copyright date:: 2014

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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