Conventional medical management of inflammatory bowel disease.

Journal article

Conventional therapies for ulcerative colitis and Crohn's disease (CD) include aminosalicylates, corticosteroids, thiopurines, methotrexate, and anti-tumor necrosis factor agents. A time-structured approach is required for appropriate management. Traditional step-up therapy has been partly replaced during the last decade by potent drugs and top-down therapies, with an accelerated step-up approach being the most appropriate in the majority of patients. When patients are diagnosed with CD or ul...

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Authors: Burger, D; Travis, S

• Publication status: Published
• Journal: Gastroenterology
• Volume: 140
• Issue: 6
• Pages: 1827-1837.e2
• Publication date: 2011-05-01
• DOI: 10.1053/j.gastro.2011.02.045
• EISSN: 1528-0012
• ISSN: 0016-5085
• Language: English
• Keywords: Remission Induction; Adrenal Cortex Hormones; Dose-Response Relationship, Drug; Proctitis; Algorithms; Anti-Inflammatory Agents; Disease Progression; Crohn Disease; Colitis, Ulcerative; Severity of Illness Index; Anti-Inflammatory Agents, Non-Steroidal; Tumor Necrosis Factor-alpha; Drug Administration Schedule; Mesalamine; Humans; Colitis