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A four-kallikrein panel predicts prostate cancer in men with recent screening: data from the European Randomized Study of Screening for Prostate Cancer, Rotterdam.

Abstract:

PURPOSE: We have developed a statistical prediction model for prostate cancer based on four kallikrein markers in blood: total, free, and intact prostate-specific antigen (PSA), and kallikrein-related peptidase 2 (hK2). Although this model accurately predicts the result of biopsy in unscreened men, its properties for men with a history of PSA screening have not been fully characterized. EXPERIMENTAL DESIGN: A total of 1,501 previously screened men with elevated PSA underwent initial biopsy du...

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Authors


Vickers, AJ More by this author
Cronin, AM More by this author
Roobol, MJ More by this author
Savage, CJ More by this author
Peltola, M More by this author
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Journal:
Clinical cancer research : an official journal of the American Association for Cancer Research
Volume:
16
Issue:
12
Pages:
3232-3239
Publication date:
2010-06-05
DOI:
EISSN:
1557-3265
ISSN:
1078-0432
URN:
uuid:f236751d-ce3b-4710-bd8b-f215d7d7cdea
Source identifiers:
365901
Local pid:
pubs:365901

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