Journal article

Efficient RNA synthesis by in vitro transcription of a triazole-modified DNA template.

Abstract:: A DNA strand containing a triazole phosphodiester mimic is an efficient template for in vitro transcription. This is the first demonstration of transcription through a heavily modified DNA backbone linkage and it suggests that click-ligated DNA could be useful for the direct synthesis of biologically active RNA and proteins.

Publication status:: Published

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APA Style

el-Sagheer, A., & Brown, T. (2011). Efficient RNA synthesis by in vitro transcription of a triazole-modified DNA template. Chemical Communications, 47(44), 12057–12058.

MLA Style

el-Sagheer, A, and T Brown. “Efficient RNA Synthesis by in Vitro Transcription of a Triazole-Modified DNA Template.” Chemical Communications, vol. 47, no. 44, 2011, pp. 12057–58.

Chicago Style

el-Sagheer, A, and T Brown. 2011. “Efficient RNA Synthesis by in Vitro Transcription of a Triazole-Modified DNA Template.” Chemical Communications 47 (44): 12057–58.
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Publisher copy:: 10.1039/c1cc14316f

Authors

+ el-Sagheer, A More by this author

Role:: Author

+ Brown, T More by this author

Institution:: University of Oxford
Division:: MPLS
Department:: Chemistry
Sub department:: Organic Chemistry
Role:: Author

Journal:: Chemical Communications More from this journal
Volume:: 47
Issue:: 44
Pages:: 12057-12058
Publication date:: 2011-11-01
DOI:: 10.1039/c1cc14316f
EISSN:: 1364-548X
ISSN:: 1359-7345

Language:: English
Keywords:: RNA

Viral Proteins

Transcription, Genetic

Click Chemistry

DNA-Directed RNA Polymerases

DNA

Triazoles
Pubs id:: pubs:399987
UUID:: uuid:f2229d77-4304-4278-92de-3dc688bf34a9
Local pid:: pubs:399987
Source identifiers:: 399987
Deposit date:: 2013-11-16
ARK identifier:: ark:/29072/ora_f2229d774304427892de3dc688bf34a9

Terms of use

Copyright date:: 2011

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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