Journal article
Morphological effects of G-quadruplex stabilization using a small molecule in zebrafish.
- Abstract:
-
Zebrafish (Danio rerio) embryos are transparent and advantageous for studying early developmental changes due to ex utero development, making them an appropriate model for studying gene expression changes as a result of molecular targeting. Zebrafish embryos were injected with a previously reported G-quadruplex selective ligand, and the phenotypic changes were recorded. We report marked discrepancies in the development of intersegmental vessels. In silico analysis determined that the putative...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Publisher copy:
- 10.1021/bi4009352
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Authors
Funding
+ Council of Scientific and Industrial Research
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Funding agency for:
Lalwani, M
Department of Science and Technology, Ministry of Science and Technology
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Bibliographic Details
- Publisher:
- ACS Publications Publisher's website
- Journal:
- Biochemistry Journal website
- Volume:
- 53
- Issue:
- 7
- Pages:
- 1117-1124
- Publication date:
- 2014-02-01
- DOI:
- EISSN:
-
1520-4995
- ISSN:
-
0006-2960
- Source identifiers:
-
472431
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:472431
- UUID:
-
uuid:f21d5bf4-af7d-42e3-82f6-7bb31db3ec77
- Local pid:
- pubs:472431
- Deposit date:
- 2014-07-09
Terms of use
- Copyright holder:
- American Chemical Society
- Copyright date:
- 2014
- Notes:
- © 2014 American Chemical Society. The full text of this article is not available in ORA.
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