Zebrafish (Danio rerio) embryos are transparent and advantageous for studying early developmental changes due to ex utero development, making them an appropriate model for studying gene expression changes as a result of molecular targeting. Zebrafish embryos were injected with a previously reported G-quadruplex selective ligand, and the phenotypic changes were recorded. We report marked discrepancies in the development of intersegmental vessels. In silico analysis determined that the putative...Expand abstract
- Publication status:
- Peer review status:
- Peer reviewed
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- Copyright holder:
- American Chemical Society
- Copyright date:
- © 2014 American Chemical Society. The full text of this article is not available in ORA.
Morphological effects of G-quadruplex stabilization using a small molecule in zebrafish.
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