Disentangling fetal and maternal susceptibility for pre-eclampsia: a British multicenter candidate-gene study.

Journal article

The Genetics of Pre-Eclampsia (GOPEC) collaboration aims to identify genetic factors in U.K. families affected by pre-eclampsia. A number of genetic studies have reported associations with pre-eclampsia, but attempts to replicate these findings have yielded inconsistent results. We describe the results of extensive genotyping of seven candidate genes previously reported as conferring susceptibility to pre-eclampsia. Six hundred fifty-seven women affected by pre-eclampsia and their families we...

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Authors: GOPEC Consortium

• Journal: American journal of human genetics
• Volume: 77
• Issue: 1
• Pages: 127-131
• Publication date: 2005-07-01
• DOI: 10.1086/431245
• EISSN: 1537-6605
• ISSN: 0002-9297
• Language: English
• Keywords: Pre-Eclampsia; Male; Great Britain; Female; GOPEC Consortium; Fetus; Genetic Predisposition to Disease; Genotype; Humans; Adult; Pregnancy