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General synthesis of sugar-derived azepane nitrones: precursors of azepane iminosugars.

Abstract:
A general and efficient method has been developed for the synthesis of sugar-derived azepane nitrones starting from aldohexoses, with an intramolecular condensation of aldehyde and hydroxylamine as the key step. Through this strategy, each aldohexose produced a pair of azepane nitrones, which are precursors of various azepane iminosugars.
Publication status:
Published

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Publisher copy:
10.1021/jo400130p

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Journal:
Journal of organic chemistry More from this journal
Volume:
78
Issue:
7
Pages:
3208-3221
Publication date:
2013-04-01
DOI:
EISSN:
1520-6904
ISSN:
0022-3263


Language:
English
Keywords:
Pubs id:
pubs:405083
UUID:
uuid:f1ee9f5d-deb2-44d1-beed-152adb0f7e9b
Local pid:
pubs:405083
Source identifiers:
405083
Deposit date:
2013-11-17
ARK identifier:

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