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Palladium catalysed elaboration of codeine and morphine

Abstract:
Palladium catalysed coupling reactions of 6-O-tert-butyldimethylsilyl-1-bromocodeine and 6-O-tert-butyldimethylsilyl-3-trifluoromethylsulfonylmorphine allow a range of substituted analogues of codeine in the 1-position and morphine in the 3-position to be efficiently and selectively prepared.
Publication status:
Published

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Publisher copy:
10.1039/b102581n

Authors

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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author


Journal:
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 More from this journal
Issue:
12
Pages:
1413-1420
Publication date:
2001-01-01
DOI:
EISSN:
1364-5463
ISSN:
1472-7781


Language:
English
Pubs id:
pubs:110599
UUID:
uuid:f1ddfc5f-7005-4fac-afb9-d6c6b74ddb55
Local pid:
pubs:110599
Source identifiers:
110599
Deposit date:
2012-12-19
ARK identifier:

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