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Journal article

T cell activation Rho GTPase activating protein (TAGAP) is upregulated in clinical and experimental arthritis

Abstract:

Genome-wide association studies have identified various susceptibility variants and loci associated with incidence of rheumatoid arthritis (RA) in different populations. One of these is T cell activation Rho GTPase activating protein (TAGAP). The present study sought to measure the expression of TAGAP in RA patients, CD4+ T cells subsets from healthy humans and in mice with collagen-induced arthritis. Peripheral blood mononuclear cells (PBMC) from RA patients and tissues of arthritic mice at ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.cyto.2017.10.002

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS; KIR
Role:
Author
More from this funder
Name:
International Research Support Initiative Program from the Higher Education Commission, Pakistan
Funding agency for:
Arshad, M
Grant:
G0601617
More from this funder
Name:
Biotechnology and Biological Sciences Research Council
Funding agency for:
Borghese, F
Publisher:
Elsevier
Journal:
Cytokine More from this journal
Volume:
104
Pages:
130-135
Publication date:
2017-10-07
Acceptance date:
2017-10-02
DOI:
EISSN:
1096-0023
ISSN:
1043-4666
Pmid:
29017772
Language:
English
Keywords:
Pubs id:
pubs:735205
UUID:
uuid:f1c1ab06-18d2-4a6c-9531-e37f11841d99
Local pid:
pubs:735205
Source identifiers:
735205
Deposit date:
2017-10-15

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