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High rates of recombination in otitis media isolates of non-typeable Haemophilus influenzae.

Abstract:

Non-typeable (NT) or capsule-deficient, Haemophilus influenzae (Hi) is a common commensal of the upper respiratory tract of humans and can be pathogenic resulting in diseases such as otitis media, sinusitis and pneumonia. The lipopolysaccharide (LPS) of NTHi is a major virulence factor that displays substantial intra-strain and inter-strain variation of its oligosaccharide structures. To investigate the genetic basis of LPS variation we sequenced internal regions of each of seven genes requir...

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Publication status:
Published

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Authors


Stringer, S More by this author
Deadman, ME More by this author
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Journal:
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases
Volume:
3
Issue:
1
Pages:
57-66
Publication date:
2003-05-05
DOI:
EISSN:
1567-7257
ISSN:
1567-1348
URN:
uuid:f1bdeb0a-5f2b-4b96-b9c9-7d1853da3581
Source identifiers:
115615
Local pid:
pubs:115615

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