Imipramine and alprazolam effects on stress test reactivity in panic disorder.

Journal article

The reactivity of 40 panic disorder patients on mental arithmetic, cold pressor, and 5% CO2 inhalation stressors was tested before and after 8 weeks of treatment with imipramine, alprazolam, or placebo. Mean levels of subjective and physiological stress measures were compared during a baseline before any stressors were given, and at anticipation, stressor, and recovery periods for each stressor. After treatment, imipramine patients differed from the other two treatment groups on the prestress...

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Authors: Roth, W; Margraf, J; Ehlers, A; Haddad, J; Maddock, R

• Publication status: Published
• Journal: Biological psychiatry
• Volume: 31
• Issue: 1
• Pages: 35-51
• Publication date: 1992-01-01
• DOI: 10.1016/0006-3223(92)90005-k
• EISSN: 1873-2402
• ISSN: 0006-3223
• Language: English
• Keywords: Panic Disorder; Psychiatric Status Rating Scales; Galvanic Skin Response; Stress, Psychological; Anxiety; Arrhythmias, Cardiac; Cold Temperature; Humans; Carbon Dioxide; Imipramine; Adult; Female; Male; Lipids; Heart Rate; Alprazolam; Respiratory Function Tests; Blood Pressure; Mental Processes; Exercise Test