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A quantitative description of components of in vitro morphometric change in the rat osteoclast model: relationships with cellular function.

Abstract:

We describe the in vitro morphometric changes shown by rat osteoclasts that accompany their functional responses to the application of a range of regulatory agents of known physiological importance. We introduce a cellular motility parameter, mu, which was defined through a quantification of retraction-protrusion behaviour. This was used in conjunction with a net cell retraction, rho, which is derived from the change in total cell area following the application of an agent. These terms were u...

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Publisher copy:
10.1007/bf00188348

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Publisher:
Springer-Verlag
Journal:
European biophysics journal : EBJ
Volume:
21
Issue:
5
Pages:
349-355
Publication date:
1992-01-01
DOI:
EISSN:
1432-1017
ISSN:
0175-7571
URN:
uuid:f1a4e660-0f57-42b6-9acb-9c71e99a4bf3
Source identifiers:
475727
Local pid:
pubs:475727

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