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Antifibrinolytics (lysine analogues) for the prevention of bleeding in people with haematological disorders

Abstract:

Review question

We evaluated the evidence about whether giving antifibrinolytics (tranexamic acid or epsilon-aminocaproic acid) to people with a low platelet count prevents bleeding and whether these antifibrinolytics are associated with side effects. Our target population was people with haematological disorders who have a low platelet count and would usually be treated with platelet transfusions. We did not include people with immune thrombocytopenia because they are not usually...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, RDM Clinical Laboratory Sciences
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM, RDM Clinical Laboratory Sciences
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM, RDM Clinical Laboratory Sciences
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
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NHS Blood and Transplant More from this funder
National Institute of Health Research More from this funder
Publisher:
Cochrane Collaboration Publisher's website
Journal:
Cochrane Database of Systematic Reviews Journal website
Volume:
2016
Issue:
3
Chapter number:
CD009733
Publication date:
2016-03-05
DOI:
ISSN:
1469-493X
URN:
uuid:f191833d-0326-443d-9fb4-a62212fa69b9
Source identifiers:
610643
Local pid:
pubs:610643

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