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Studies on the use of hollow fibre membrane bioreactors for tissue generation by using rat bone marrow fibroblastic cells and a composite scaffold.

Abstract:

Production of sufficient tissue in vitro for use in tissue engineering is limited mainly by the absence of adequate oxygenation and appropriate transport of nutrients to, and waste product from, the tissue. To overcome the limitations of diffusive transport, the possibility of growing three dimensional (3D) tissue structures by using hollow fibre membrane bioreactors (HFMB) has been considered in this study. The hollow fibre membranes, embedded in the 3D scaffold, are porous and semi-permeabl...

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Publication status:
Published

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Publisher copy:
10.1007/s10856-007-2314-4

Authors


Ferguson, DJ More by this author
Triffitt, JT More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Engineering Science
Journal:
Journal of materials science. Materials in medicine
Volume:
18
Issue:
4
Pages:
641-648
Publication date:
2007-04-05
DOI:
EISSN:
1573-4838
ISSN:
0957-4530
URN:
uuid:f16dfd74-df9f-4c92-acf3-95950c19ebd9
Source identifiers:
62003
Local pid:
pubs:62003

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