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Journal article

Pitfalls of clinical trials on pharmacological treatment for obstructive sleep apnoea: future directions.

Abstract:

The standard treatment for obstructive sleep apnoea (OSA) is continuous positive airway pressure (CPAP). Depending on selection criteria and quality of care, up to 50% of patients with OSA do not tolerate CPAP. For patients who cannot tolerate CPAP despite good quality care, pharmacological treatment would be a desirable alternative. The mechanisms by which pharmacological treatment is supposed to improve OSA include, amongst others, an augmentation in pharyngeal dilator muscle tone, an incre...

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Publication status:
Published

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Journal:
Expert opinion on investigational drugs
Volume:
20
Issue:
8
Pages:
1033-1037
Publication date:
2011-08-05
DOI:
EISSN:
1744-7658
ISSN:
1354-3784
URN:
uuid:f14e3b14-ba28-4a12-aade-ff906fe57e63
Source identifiers:
151185
Local pid:
pubs:151185

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