Regulatory T cells in transplantation.

Journal article

There has recently been an explosion of renewed interest in regulatory T cells, particularly those within the CD4(+)CD25(+) population. It is becoming increasingly apparent that these cells exist not only as naturally occurring cells that may contribute to the maintenance of self-tolerance, but they also have the potential to prevent rejection of allografts in experimental models. Such cells have now been identified in humans as well as in rodents.

Authors: Karim, M; Bushell, A; Wood, K

• Publication status: Published
• Journal: Current opinion in immunology
• Volume: 14
• Issue: 5
• Pages: 584-591
• Publication date: 2002-10-01
• DOI: 10.1016/s0952-7915(02)00379-5
• EISSN: 1879-0372
• ISSN: 0952-7915
• Language: English
• Keywords: Humans; Isoantigens; Cytokines; Receptors, Interleukin-2; Immunophenotyping; Interleukin-2; Transplantation Immunology; Animals; Antigens, CD45; T-Lymphocytes