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Genetic hitchhiking in spatially extended populations.

Abstract:

When a mutation with selective advantage s spreads through a panmictic population, it may cause two lineages at a linked locus to coalesce; the probability of coalescence is exp(-2rT), where T∼log(2Ns)/s is the time to fixation, N is the number of haploid individuals, and r is the recombination rate. Population structure delays fixation, and so weakens the effect of a selective sweep. However, favourable alleles spread through a spatially continuous population behind a narrow wavefront; ances...

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Publication status:
Published

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Publisher copy:
10.1016/j.tpb.2012.12.001

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Institution:
University of Oxford
Department:
Oxford, MPLS, Statistics
Role:
Author
Journal:
Theoretical population biology
Volume:
87
Pages:
75-89
Publication date:
2013-08-05
DOI:
EISSN:
1096-0325
ISSN:
0040-5809
URN:
uuid:f1381da9-3caf-4f81-a4df-a74a641404a5
Source identifiers:
379466
Local pid:
pubs:379466
Language:
English
Keywords:

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