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The TP53 colorectal cancer international collaborative study on the prognostic and predictive significance of p53 mutation: influence of tumor site, type of mutation, and adjuvant treatment.

Abstract:

PURPOSE: The aims of the TP53 Colorectal Cancer (CRC) International Collaborative Study were to evaluate the possible associations between specific TP53 mutations and tumor site, and to evaluate the prognostic and predictive significance of these mutations in different site, stage, and treatment subgroups. PATIENTS AND METHODS: A total of 3,583 CRC patients from 25 different research groups in 17 countries were recruited to the study. Patients were divided into three groups according to site...

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Publication status:
Published

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Publisher copy:
10.1200/jco.2005.00.471

Authors


Iacopetta, B More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Clinical Lab Sciences, Biomedical Research Centre
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Journal:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Volume:
23
Issue:
30
Pages:
7518-7528
Publication date:
2005-10-05
DOI:
EISSN:
1527-7755
ISSN:
0732-183X
URN:
uuid:f12a1b9f-9cd9-4a93-85e9-64b6bc683f69
Source identifiers:
346447
Local pid:
pubs:346447

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